Preliminary Program

/Preliminary Program
Preliminary Program2019-07-09T18:58:13+00:00

2019-11-03
2019-11-03
2019-11-04
2019-11-04
2019-11-05
2019-11-05
13:00 - 17:00
Biobanking 101 Workshop

*Registration for this pre-conference workshop is in addition to general meeting registration and is priced at $95.


Learning Objectives:

  • Learn how to write a biobanking informed consent form in plain language based on published health literacy principles and toolkits
  • Identify the methods of Cold Chain Management from sample collection through processing, storage, and shipping operations
  • Describe new technologies and innovations in harmonizing approaches to evolving challenges in biological and environmental repositories
17:00 - 18:30
Welcome Reception
18:30 - 19:30
Roundtable Discussions
08:00 - 09:45
Symposium 1: Bringing it Back… to the Community: Banking on Diversity & Sharing /All of Us Spotlight

Prevention and precision medicine for all relies on biobanks and research studies that include specimens from diverse populations to answer questions that are general and that are specific for certain populations. Inclusion of diverse, under-served, and specialized populations in research requires special attention to governance structures and active approaches to community engagement. Attention to privacy and trust relationships are a significant element of success. This symposium will discuss the opportunities and challenges in precision medicine and prevention for all, community engagement, IRB governance with a highlight on the activities of All of Us Cohort and other large studies that impact communities.

09:45 - 10:15
Networking Break
10:15 - 11:45
Symposium 2: All Along the Watch Tower: Wearable Data Tracking and Direct to Consumer Genetics Data

The digital health industry has sprung up quickly in recent years. Easy access to direct-to-consumer genetics for ancestry and health risk analysis, personal digital health trackers to monitor constantly vital statistics, and lifestyle have contributed significantly to this growth. In 2018, it was predicted that venture capitalists and health systems would invest in the region of $7 billion in digital health solutions including wearables and biosensors like Fitbits, precision medicine and genomics, mobile diagnostics, and clinical decision support via telemedicine. Whilst the FDA regulates medical devices, it does not regulate all genetic services or wearable devices.

Wearable data tracking and direct to consumer genetics data have many elements in common. They enable the individual to produce vast amounts of health-related data that are an incredible source of data for research and public health, they raise privacy concerns, and they open a market for individual selling of personal data. In this session, we will discuss the implications of such bio-voyeurism, whether (and how) such data should be shared and banked for future research use and the challenges to be overcome to facilitate such sharing. We will address potential policy gaps and self-regulation recommendations required to ameliorate privacy concerns and other ethics and governance issues related to big data banking.

12:00 - 13:00
Corporate Workshops 1 & 2
13:00 - 13:30
Lunch with Exhibits
13:30 - 14:30
Corporate Workshops 3 & 4
14:45 - 16:15
Symposium 3: Don’t think twice, it’s alright! There Are Many Roads to Sustainability

Sustainability is a complex and ongoing challenge for most biobanks around the world. A biobank’s mission, sample types, numbers and types of stakeholders served and source(s) of funding, impacts the importance of sustainability in a biobank’s business plan. Furthermore, sustainability issues encompass all financial, social and operations aspects of a biobank. This session will be an interactive moderated discussion with representatives of four different Minnesota biobanks across biobanking sectors, including human, non-human and environmental samples, that have achieved sustainability. Each speaker will clearly describe their biobank’s mission, essential elements, sample and stakeholder statistics and operating principles. The moderator(s) will engage with all speakers in a ‘talk show style’ to elicit information of how they define successful sustainability and the challenges and lessons learned in achieving it. Audience participation will be encouraged.

16:15 - 16:45
Networking Break
16:45 - 18:30
Symposium 4B: “All I really want to do”… is share data with you: Regulations for Data Sharing and International Collaborations

Recent regulatory changes both in the US and abroad contain requirements that may hinder data sharing and impede international reasearch collaborations. Differences among the various regulations may cause conflicts in requirements for data handling once shared, due to the content and scope of the applicable regulations. The EU-General Data Protection Regulations recently implemented on May 25, 2018 has broad territorial reach outside of the EU and is significantly affecting multinational studies involving personal data from EU citizens or held by EU entities. While the regulations allow data sharing with countries such as the US when there is appropriate legal basis, many of these approaches have considerable challenges. Furthermore, significant differences among the EU-GDPR, Common Rule, and Health Insurance Portability and Accountability Act (HIPAA) are also creating implementation challenges for those wishing to share to data internationally. This session will provide an overview of these challenges and discuss attempts at resolutions. In addition, case studies in international collaborations will be discussed as well as proposed approaches to address the challenges in an interactive panel session.

Speakers:

“I ain’t lookin’ to block you up”: International collaboration and data flow under the EU GDPR

Heidi Beate Bentzen, LLM, University of Oslo

Title TBD

David Peloquin, JD, Ropes & Gray LLP

16:45 - 18:30
Symposium 4A: Tangled up in Trypan Blue: Living Biobanks

Tissues, gametes and isolated cells from humans, plants, and animals may be preserved in a manner as to preserve viability and function. Retaining viability and function for a biospecimen presents specific challenges for biobankers. This session is designed to address unique challenges of preserving specific high-value biospecimens, as well as overall challenges with workflow, quality assessment, and downstream uses of specimens from living biobanks.

Speakers:

Patient Derived Xenografts for Modeling Ovarian Cancer Chemotherapy Resistance

Tim Starr, PhD, University of Minnesota

Germplasm Cryobanking for Biomedical Research

Yuksel Agca, DVM, PhD, University of Missouri

Establishing an Off-the-Shelf Supply of Living Tissues

Jedd Lewis, JD, Organ Preservation Alliance

 

18:30 - 20:00
Networking Reception and Poster Session
08:00 - 09:30
Educational Workshop 1
08:00 - 09:30
Symposium 5: Forever Young? Biospecimen Quality to Ensure Longevity

Biobanks are only as relevant as the specimens that are housed within them. Preanalytical variables have the power to change specimen quality and integrity, which can alter downstream data. This session will review why quality measures are relevant, highlight some of the current standards, and provide state-of-the-science preanalytical quality measures. Attendees should expect to learn how and why to formulate and implement a quality management program for their own repositories.

Speakers:

Title TBD

Stephen Hewitt, National Cancer Institute

Effect Of Pre-Analytic Variables On Established And Emerging Thrombosis-Related Biomarkers In An Ethnically and Racially Diverse Population Of Cancer Patients and Healthy Subjects At A Safety Net Hospital

Elizabeth Duffy, MA, Boston Medical Center

Delta-S-Cys-Albumin: A Lab Test that Quantifies Cumulative Exposure of Archived Human Blood Plasma and Serum Samples to Thawed Conditions

Chad Borges, PhD, Arizona State University

09:30 - 10:00
Networking Break
10:00 - 11:30
Contributed Paper Sessions 1 & 2
11:45 - 13:15
Corporate Lunch Symposium
13:30 - 15:15
Symposium 6B: Integrating Digital Biospecimens – don’t leave them “Blowin in the Wind”

Digital pathology, along with digital radiology imaging systems, is becoming the new norm within clinical digital imaging. They are an incredible resource for immediate review of disease status and tissue samples. This session will focus on digital imaging from radiology and pathology, and its potential as a biobanking and research resource to not only catalogue disease but also be used as a diagnostic tool and a tool to track the progression of disease and/or recovery. This session will also explore the innovative area of digital imaging as a learning tool to develop artificially intelligent (AI) systems and the potential use of AI systems to provide quality control, analysis of sample composition, and computer assisted evaluation of disease.

13:30 - 15:15
Symposium 6A: Shelter from the Storm – Keeping Biospecimens Alive

Keeping heterogeneous systems alive is a particular challenge for living biobanks. Speakers in this session will expand upon the challenges outlined in Symposium 4A: “Tangled up in Trypan Blue: Living Biobanks” to include challenges of preserving heterogeneous systems such as microbiome, human tumors, and other biospecimens containing numerous cell types.

Speakers:

The RAMS Registery/Repository: Biobanking for Microbiome Research in Women’s Reproductive Health and Pregnancy

Gregory Buck, PhD, Virginia Commonwealth University

Biobanks in LMIC: Global Efforts needed to foster Pediatric Research

Rania Labib, PhD, Children’s Cancer Hospital-57357-Egypt

Conditionally Reprogrammed Normal and Tumor Cells -Living Biobanks- for Personalized Medicine

Xuefeng Liu, MD, Lombardi Comprehensive Cancer Center, Georgetown University

15:15 - 15:45
Networking Break
15:45 - 17:15
Educational Workshops 2 & 3 & 4
17:15 - 17:30
Closing Ceremony
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